Gut Immunity And Colonic Lymphoid Aggregates: A Comprehensive Overview
Colonic lymphoid aggregates (CLAs) are crucial for gut immunity, comprising Peyer’s patches, isolated lymphoid follicles, and cryptopatches. Their germinal centers facilitate antibody production, while T cell zones support immune responses. The specialized follicle-associated epithelium (FAE) allows antigen sampling through M cells. Dendritic cells play a key role in antigen presentation. Colonic Lymphoid Aggregates: Guardians of …
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