Ultra-High Performance Liquid Chromatography (Uhplc): Benefits, Capabilities, And Cost Considerations
UHPLC employs higher pressure, smaller column dimensions, and sub-2 μm particles, enabling faster separations and improved detection sensitivity compared to HPLC. UHPLC’s smaller column dimensions enhance sample throughput, while the sub-micron particles offer higher surface area and better mass transfer. Higher pressure in UHPLC overcomes the increased flow resistance of smaller particles, resulting in faster …